melanotic mucosa in the entire colon MELANOSIS COLI** Melanosis coli is a disorder of pigmentation of bowel wall. Histology demonstrates pigment-laden macrophages It is associated with laxative abuse, especially **anthraquinone compounds such as senna** Frontiers | Case report: Melanosis

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Contraindications/Precautions Cyanocobalamin is contraindicated in those with hypersensitivity to cobalt moiety or cobalamin molecule due to the risk of anaphylaxis (9)

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treat promptly per standard of care, and monitor until signs and symptoms resolve

Usually found in mixed forest margins with dappled sunlight on the banks of a sandy brook or stream (25)