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Nonetheless, these symptoms led to discontinuation of treatment in 4-8% of patients enrolled in completed obesity trials for semaglutide (Novo Nordisk), and the dual GLP-1/GIP receptor agonist tirzepatide (Eli Lilly)

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CAP-induced TRPV1 calcium responses were again inhibited by pretreatment with GLP-1 analogs or exendin 939 (Fig

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Zepbound has also been shown to be more effective than Wegovy in clinical trials