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Dual inhibition of IL-4 and IL-13 signaling helps 1-5 : REDUCE TYPE 2 INFLAMMATION RELIEVE ITCH Helps relieve itch-scratch cycle ACHIEVE CLEARER SKIN Helps improve skin barrier function Helps improve skin lesions The mechanism of dupilumab action has not been definitively established

When used in combination with exercise and diet, GLP-1 drugs can be helpful to some patients, Small said

While its not a widely recognized side effect nor is it even reported in clinical trials understanding why sleep disturbances and issues might happen during treatment can help you manage them better

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doi: 10.3389/fmolb.2025.1724944 Received 14 October 2025 Revised 18 November 2025 Accepted 30 November 2025 Published 18 December 2025 Volume 12 - 2025 Edited by Maria Barile, University of Bari Aldo Moro, Italy Reviewed by Anna Maria Giudetti, University of Salento, Italy Maria Tolomeo, National Research Council (CNR), Italy Updates Copyright 2025 Schrder, Jalilvand, Kahl, Kaiser and Liebau