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Most GLP-1 medications should be stored in the refrigerator at: 36F46F (2C8C) This applies to: Ozempic Wegovy Mounjaro Zepbound Trulicity Victoza Saxenda Byetta / Bydureon Refrigeration protects the proteins in the medication from breaking down

& Silverman, R

Also, experiments conducted in primary islet cells have shown that -arrestin1 restricts the insulin secretion response to GLP1R activation, but not to GIPR activation or tirzepatide

Your body adapted to GLP-1 agonism, but it has not adapted to GIP agonism because it has never been exposed to pharmacological GIP activation before

Your risk really comes down to whether you have underlying macular degeneration, explains Dr