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Research also indicates interaction with pro-opiomelanocortin (POMC) neurons modulation of motivational circuitry

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doi: 10.1124/pr.109.001370 170 MonteroMYonLKikuyamaSDufourSVaudryH

Dopamine (DA), a precursor for adrenaline and noradrenaline, is decreased in individuals with IBS (Mitsi and Zachariou, 2016) and psychological disorders, and it can regulate intestinal inflammation by inhibiting the NLRP3 inflammasome (Yan et al., 2015