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Spiking experiments involved addition of known amounts of pure NAD and glutathione compounds individually at different stages of the extraction (Supplementary Table 1), followed by quantification using colorimetric assays

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Adult male mice (8- and 12-weeks old) were subjected to 70% PH under ketamine/xylazine anesthesia

Mitochondrial dysfunction is closely associated with abnormal energy metabolism, inflammatory response, IR (50, 52), and the occurrence of obesity, diabetes, and chronic renal disease (5355)

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