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Efficacy of HDAC inhibitors and epigenetic modulation in the amelioration of synovial inflammation, cellular invasion, and bone erosion in rheumatoid arthritis pathogenesis

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There was a significant increase in wound contraction rate, skin breaking strength that reflected increased collagen levels

Itching is not listed as a frequent side effect in major clinical trials, but patient reports suggest it occurs in a small percentage of users, typically during the initial weeks or dose escalation phase