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Examining MT-II-induced dopamine release in the nucleus accumbens by in vivo microdialysis, studying how MC4R activation in the VTA alters dopamine neurone firing and downstream reward behaviour, and examining whether dopamine receptor antagonists attenuate the motivational components of MT-IIs pro-sexual and appetitive effects

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Glucagon-like peptide-1 (GLP-1) agonists, initially indicated for treatment of T2D, are the newest FDA-approved AOMs