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Effect of helicobacter pylori infection on glucose metabolism, lipid metabolism and inflammatory cytokines in nonalcoholic fatty liver disease patients

This study not only elucidates the mechanisms of PARP1-mediated PXR E194 ribosylation in AILI but also identifies Sch B as the first specific inhibitor of this pathway, providing a theoretical basis for precision detoxification strategies targeting posttranslational modifications

Moreover, overexpression of SLA7A11 in human tumor suppresses ROS-induced ferroptosis and inhibits p53 3 KR -mediated tumor growth suppression in xenograft models