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Squier CA, Waterhouse JP

By reducing inflammation, oxidative stress, and myocyte necrosis, LC may thus provide cardioprotective effects (710)

In contrast, organs with high sensitivity to glucocorticoids, such as the liver, adipose tissue, and skeletal muscle, highly express 11-HSD1, which catalyzes the reverse reaction of 11-HSD2, thereby increasing cortisol bioavailability (1)

Results: Berberine reduced renal injury in STZ-induced DN rat model, as evidenced by the decrease in fasting blood glucose, ratio of kidney weight to body weight, 24-h urinary protein, serum creatinine, and blood urine nitrogen

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