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Therefore, ApGST-O8 was excluded from further phylogenetic analysis

PLoS One 10 , e0125192 (2015)

Exposure to ATZ reduces the mRNA expression of steroidogenic genes ( StAR , CYP17A1 , and 17-HSD ) which is directly linked to decreased androgenesis, thus, impairs the steroidogenesis of Leydig cells 108

Because thermoneutrality minimizes the contribution of non-shivering thermogenesis to whole-body energy expenditure and because non-shivering thermogenesis requires functional brown adipose tissue (BAT) [775], these data imply a contribution of endogenous GLP-1R signaling to the control of energy expenditure, at least in diet-induced obese mice, by regulating BAT activity

But the face you see a year after surgery isnt guaranteed to be the face you have at year five if your weight changes a lot