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For this reason, the circadian changes in the endocrine components of breast milk are noteworthy [17]

These findings emphasize the need of swift freezing or analysis of the metabolites, with a maximal time of four hours of exposure to room temperature to prevent significant metabolite dynamics in vitro

Medical Management Induction of Remission: Mild-moderate disease: Budesonide (9 mg/day) for ileocolonic disease

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Despite these advances, the long-term efficacy of existing therapies diminishes over time and presents with severe adverse effects, necessitating the exploration of novel therapeutic approaches