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For more on typical intake patterns, see our guide on eating too little on Mounjaro

However, observational studies suggest that whilst acute toxicity remains exceptionally rare, sustained very high levels of B12particularly from supplements or injectionsmay be associated with certain health concerns, though these are correlations rather than proven causal relationships

a lower threshold may apply in people with type 2 diabetes)

Neurology 1998;50:645-51

Further, suppression of gut microbes with an oral antibiotic cocktail virtually eliminated plasma levels of BB, strongly indicating the majority of the analyte in L- carnitine supplemented mice was derived from gut microbial metabolism of dietary L -carnitine and not via the endogenous biosynthesis pathway