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338 doi: (Published 28 January 2009) Cite this as: BMJ 2009;338:b277 Ewan A Langan, Walport academic clinical fellow in dermatology1, Denise Ramlogan, consultant dermatologist2, Lynne A Jamieson, consultant dermatopathologist3, Lesley E Rhodes, professor of experimental dermatology1 1 Dermatological Sciences, University of Manchester, Salford Royal NHS Foundation Trust, Salford M6 8HD 2 Dermatology Centre, Salford Royal NHS Foundation Trust, Salford M6 8HD 3 Department of Cellular Pathology, Salford Royal NHS Foundation Trust, Salford M6 8HD Ewan postgrad.manchester.ac.uk We draw attention to a new factor complicating presentation and diagnosis of pigmented lesions1: unlicensed use of melanotropic peptides offered online as Melanotan I and II