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A 2012 analysis by Pickart and Margolina identified that GHK-Cu modulates the expression of over 4,000 human genes approximately one-third of all genes with a known biological function
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Evidence for this action has been demonstrated in mice (Fridolf et al., 1991), rats (de Heer et al., 2008), dogs (Freyse et al., 1997), and humans in vivo (Hare et al., 2009), as well as in intact isolated mouse islets (De Marinis et al., 2010)
Seran ideales los estudios doble ciego, controlados, con distribucin al azar, con nmero significativo de pacientes que comparen la combinacin simultnea, secuencial o ambas para evaluar si los efectos son similares y teniendo en cuenta iSGLT (especficos y duales) y AGLP1 de accin larga, corta o ambas