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GLP-1 receptor agonists (GLP-1 RAs) are newer medications that were initially released as treatment for diabetes In higher doses, they have shown promising results in weight loss also Wegovy (semaglutide) was the first GLP-1 RA approved for weight loss by the FDA Zepbound (tirzepatide) was just recently approved by the FDA Early data shows better weight loss with Zepbound/tirzepatide than Wegovy/semaglutide What are GLP-1 receptor agonists and why do they work