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Unlike the tetrameric GPx1-GPx3, the GPx4 protein is a monomer which can not only reduce hydrogen peroxide, but also distinctly react with lipid and fatty acid hydroperoxides including cholesterol derivatives, amongst many other substrates

Black and tarry stools are indicative of bleeding in the stomach or small intestine Additional symptoms may include anal, pelvic or abdominal pain, dizziness, fatigue, diarrhoea, and constipation, amongst others

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