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The medication is primarily eliminated through protein catabolism rather than traditional hepatic metabolism, meaning liver disease typically does not substantially affect elimination rates
10.1002/mnfr.201700479 Mol Nutr Food Res
PGD2 then triggers BMP signaling, which induces CXXC5 expression
This method of administering B12 allows it to bypass the digestive system, ensuring better absorption than taking a dose orally
The opposite occurs in a condition called SIADH (syndrome of inappropriate antidiuretic hormone), ADH is secreted at extremely high levels leading to extremely concentrated urine producing a dangerously low blood osmolarity known as water intoxication
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