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Subsequent clinical studies with liraglutide and semaglutide confirmed these findings, and further demonstrated the effect to be mediated via reduced energy intake

Murphy MG, Plunkett LM, Gertz BJ, He W, Wittreich J, Polvino WM, Clemmons DR

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In patients with active RA, the addition of low-dose sirolimus (0.5 mg every other day for 24 weeks) to conventional immunosuppressive therapy effectively increased Treg cell frequencies, reduced Th17 cell populations, and improved clinical disease activity (Chictr.org.cn identifier: ChiCTR-IPR-17010307) (240)

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