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PI/PC-PLC-Independent Effects of Exendin-4 While GLP-1 has been shown to regulate the phosphatidylinositol-phospholipase C (PI-PLC) or phosphatidylcholine-phospholipase C (PC-PLC) activity in mouse pancreatic cells [56], experiments with the PI-PLC inhibitor U73122 or with the PC-PLC inhibitor D609, did not support the involvement of these two pathways in the exendin-4 effects on GCs

Early evaluation helps determine whether lifestyle changes are enough or surgery is the right choice

Endocrine/metabolic Feb

PEG-MGF is selected when the research question involves satellite cell dynamics or muscle regeneration in response to mechanical or injury stimuli

Heurtaux T, Bouvier D, Bnani A, Helgueta S, Frauenknecht K, Mittelbronn M, Sinkkonen L (2022) Normal and pathological NRF2 signalling in the central nervous system