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At therapeutically and research-relevant doses, MC4R is the primary pharmacologically active receptor both because it has the highest CNS expression density in regions governing sexual behaviour and because MC1R-mediated pigmentation effects (the basis of the tanning response to MT-II) are substantially attenuated in PT-141s cyclic structure

A continuous microplate assay for sirtuins and nicotinamide-producing enzymes

Pigmented cancer cells multiply faster than normal melanocytes

C'est ce qui lui permet de contribuer la protection de lorganisme et nous maintenir en bonne sant

Because glutathione has regulatory properties on melanogenesis and antioxidants in general are protective against aging process, the dual antimelanogenic and antiaging properties demonstrated in Watanabes and our studies are not surprising