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Cardiorenal syndrome type 4: management

Vitamin C deficiency causes capillary fragility and bruising within 30-90 days of inadequate intake, while vitamin K deficiency affects clotting factor production in the liver

Proposed mechanisms include fibroblast migration and proliferation, modulation of growth-factor signalingincluding EGF and VEGFand changes in reticulin and collagen-fiber formation at injury sites

Vaccines for nontypeable Haemophilus influenzae: the future is now

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