These scientists concluded as follows: Although there are many opinions about the risks or benefits of antioxidant supplementation, the only supportable conclusions based on the present research are that there is no evidence of antioxidant supplementation causing harm alongside cancer therapy, except for smokers undergoing radiotherapy. The caveat for smokers is based on a trial in head and neck cancer patients in which supplementing with alpha-tocopherol and beta-carotene during radiotherapy had a negative impact on rates of cancer recurrence and death in participants who smoked during the trial (Meyer 2008)
Some of the primary genes impacted are COL1A1 (matrix), VEGFA (angiogenesis), IL6 (inflammation), and SOD2 (oxidative defense)
For practical context: Research has explored ranges of roughly 0.54 mg per kilogram of body weight In supplementation discussions, this often translates to single-digit to low double-digit milligram amounts per day Many liquid methylene blue products are sold as a 1% solution, which corresponds to approximately 10 mg per milliliter, allowing dosing to be measured using a dropper
10.1038/s41598-022-07381-3 Sci Rep
Moreover, GLP-1 drugs can assist in controlling individuals who take glycerine control measures to obtain low blood sugar levels, which can further support appetite suppression and weight loss
