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One challenge that tends to occur in autistic children is difficulty with metabolic processes, specifically methylation and oxidative stress 2,3

Also, its growth hormone-stimulating properties make it unsafe for people with active cancer ,27 and its action on the pituitary gland means its unsuitable for people with a pituitary gland disorder

Further, NICE and the BNF says that if there are neurological symptoms present, then every other day injections are the recommended treatment, so all the points you make about B12 being stored and sufficient are not really relevant

The 2000 survey of the experimentally verified IDPs included 16 proteins, whose extended conformation was evidenced by the abnormal mobility on gel-filtration column ( Uversky et al., 2000a ), supporting the idea that SEC played an important role in establishing the commonness of IDPs

Adenosylcobalamin functions in mitochondria as a cofactor for methylmalonyl-CoA mutase