Preparation methods, including thin-film hydration, emulsion solvent evaporation, nanoprecipitation, and self-assembly, critically influence the particle size, morphology, and surface ligand distribution
doi: 10.1001/jama.2019.2941 140 NauckMA
Since GLP-1 medications mimic the action of a peptide produced in the GI tract, most reported mild side effects are associated with the digestive tract
Common side effects include nausea, vomiting, diarrhoea, and abdominal discomfort, particularly during treatment initiation
[DOI] [PubMed] [Google Scholar] 70.A study of tirzepatide (LY3298176) compared with dulaglutide on major cardiovascular events in participants with type 2 diabetes (SURPASS-CVOT)