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Under conditions of low glucose, oxidative stress, or inflammation, mitochondria increase production of MOTS-C, which then: Enters the nucleus to modulate transcription of genes associated with antioxidant defenses, such as NRF2 targets

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(They classify it as a medicinal product because of its composition and how its administered by injection.) Lemon Bottle does not have US FDA approval, nor does it have the European/UK CE mark for medical devices (I would expect this as a minimum says Tonks)

It also provides the clinical foundation for asking whether adding glucagon receptor activation can further increase efficacy

Nutrition 2015 Jun 1