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Singh et al., 2010

Re-titrating from a lower dose supports smoother reintroduction

It establishes that DSIP can cross into CSF but it also identifies plasma half-life as one of the three determinants of how much gets in

By choosing B12 shots, you are not just investing in a supplement

To improve transparency, an adapted PRISMA-style flow diagram documenting identification, screening, eligibility assessment, de-duplication, and selection of the RCT evidence base and the proof-of-concept Bayesian subset is provided in the Supplementary Appendix Figure 1, together with details of the search strategy, screening process, and data extraction