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Below 2.5V you will start to damage the LiPo, and below 3.0V you will shorten its useful cycles

Similarly, excessive ER- receptors in the endothelial cells of the uterine microvasculature induce cyclooxygenase (COX) and prostaglandin-E2 (PGE 2 ) [72]

Further clinical research is warranted to optimize dosing regimens and validate long-term efficacy

For split dosing, which maintains the same total weekly dose, mathematical models suggest efficacy maintenance of 80% to 95%

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