Odorranalectin-conjugated nanoparticles: preparation, brain delivery and pharmacodynamic study on Parkinsons disease following intranasal administration
These disorders can be associated with insulin resistance, hyperglycemia-induced damage, oxidative stress, astrocyte abnormalities, and mitochondrial dysfunction, resulting in insufficient energy supply, altered synaptic plasticity, death of neuronal cells, as well as functional and structural damage to reward networks
Combination of alpha lipoic acid and superoxide dismutase leads to physiological and symptomatic improvements in diabetic neuropathy
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The common therapeutic approach for these disorders is aimed at regulating circulating GH and IGF-1 levels using recombinant hormone therapy,8 but ongoing in vitro and in vivo studies are employing newer methods of treatment