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Some retrospective analyses suggest patients using GLP-1 medications may experience fewer RA flares or reduced inflammatory markers compared to those on other diabetes treatments

There is no strong evidence of GLP-1 drugs directly interfering with folate absorption

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In the mitochondria of DRGs, the glucose oxidation brought on by diabetes mellitus (STZ) causes an intracellular free Ca 2+ and Zn 2+ influx excess that is dependent on TRPV4