01 Gastric Pentadecapeptide Synthetic 15-amino-acid peptide derived from human gastric juice protein 02 99% HPLC Purity Every batch verified via high-performance liquid chromatography 03 USA Tested & Verified Third-party analytical testing performed in USA laboratories RESEARCH BPC-157 Mechanism of Action in Research The BPC-157 mechanism of action has been a central focus of preclinical research for over two decades
Citi V, Torre S, Flori L, Usai L, Aktay N, Dunford NT, et al
It cleaves the oligo-peptides after the 2nd amino acid from the N terminal proline or alanine sequences, thus rendering GLP-1 and GIP inactive ( in vivo through dipeptide cleavage (Mentlein et al., 1993)
Treatment allocation was masked from the participant and investigators and a double check of allocation was performed by an unblinded nurse and pharmacist
Approximately 50% of HMBi is shielded from ruminal degradation, with the remaining 50% undergoing hydrolysis by rumen microorganisms to HMB and isopropanol (Graulet et al., 2005)