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In one case, a 37-year-old male developed new neck and back pain after increasing from 7.5 mg to 10 mg

The majority of QIs was reduced back to the respective parent compound (50% of AQ-QI and 80% of DEAQ-QI), presumably by the action of endogenous antioxidants and/or reductases, e.g., quinone reductases ( Figure 5B )

Break of 5 weeks or more (including 3 months): Restart at the lowest dose, 0.25 mg weekly

Important : This medicine can cause persistent and severe tummy (abdominal) pain with sickness (nausea and/or vomiting) in a few people

The argument is not that a single early appointment is a strain, but that the precedent of making such exceptions could be