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pooled safety database: Schneck CPT:PSP 2024

Simpson R, Devenyi GA, Jezzard P, Hennessy TJ, Near J

Making them involves special chemicals called coupling agents, which can trigger serious allergic reactions, including anaphylaxis a life-threatening condition

Although these therapeutic approaches have demonstrated promise in preclinical studies, no DMT drugs have yet received approval, and many candidate drugs have failed to achieve primary endpoints in clinical trials