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Interestingly, SOD activity is not affected by continuous sun exposure

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In China, supportive policies like accelerated approval pathways for urgently needed orphan drugs (UNOD) and Care for Rare Diseases Encouragement (CARE) plan 28 , have been implemented to improve access to therapies for rare conditions

These findings support the relevance of MGBA mechanisms in BD pathophysiology, implicating both immune and metabolic pathways as shown in Table 8, and are conceptually illustrated through the microbiotaimmunemetabolicbrain axis model (Figure 6