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So while berberine can offer support, its effects are generally milder than prescription medications, and results can vary quite a bit from person to person

Both are GHRH-receptor agonists that raise endogenous GH and IGF-1, but tesamorelin has far stronger and more recent human data than sermorelin

The analysis was limited to a 6-month follow-up period, which may not capture the full magnitude or durability of treatment effects, as clinical trial data suggest that weight reduction typically continues beyond 6 months and often does not plateau until approximately 36 weeks or later, even at lower doses [24]

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Tesamorelin's GHRH mechanism is tissue-specific to the pituitary