[] The neurotoxin anxiogenic consequences of cisplatin, a drug frequently used in oncology, are caused by elevated oxidative stress
Sleep Architecture and Delta-Wave Promotion: In rabbit, rat, cat, and limited human EEG studies, intravenous or intracerebroventricular DSIP administration significantly increased total sleep time, prolonged slow-wave sleep (SWS) duration, increased delta-wave power, and reduced sleep latency without altering REM sleep proportion
It should be emphasised, however, that this does not constitute a scientifically validated protocol or a recommendation for use
10.1186/s12864-021-08159-z BMC Genomics
For preclinical research this matters, because it allows the release of growth hormone to be studied without parallel rises in stress hormones confounding the interpretation