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LRG1: leucine-rich -2 glycoprotein 1

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These reactions are often dose-dependent and may subside as the body acclimates to therapy

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In hepatic encephalopathy, elevated blood ammonia resulting from liver failure disrupts the BBB via the Nuclear Factor -Light-Chain-Enhancer of Activated B Cells (NF-B) pathway, impairs mitochondrial function in astrocytes, and perturbs neurotransmitter balance through potassium dysregulation [67]