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Novo Nordisk also began recruiting a roughly 900-site Phase 3 heart-failure trial for amycretin (zenagamtide) and opened a $50-a-month Medicare bridge for Wegovy

Cortisol and semaglutide: Exploring the endocrine effects of GLP-1 analogues

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For comparing GLP-1RAs with metformin, the study population was divided into a GLP-1RA/no metformin group (32 365 patients prescribed a GLP-1RA but not metformin) and a metformin/no GLP-1RA group (856 160 patients prescribed metformin but not GLP-1RAs) (Figure 1)