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Collectively, these findings highlight cotadutides dual benefits for glycemic control and liver health, supporting its further development for T2D, obesity, and NASH treatment [85]

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However, in light of known complications of these devices, including bleeding, 40 and lack of evidence of long-term benefit in terms of mortality rates, their use has come under debate

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Clinicians should adopt an individualized approach, considering patient-specific factors such as age, reproductive plans, comorbidities, and tolerance