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Much of the purported clinical utility is derived from anecdotal accounts or small, uncontrolled series, rather than from robust randomized trials

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Retrieved from Mars, J

First authorized for type 2 diabetes and then obesity, GLP-1 RAs such as liraglutide and semaglutide suppress appetite, increase insulin sensitivity, and reduce weight by significant amounts that make a difference to fertility

Our bodies naturally produce creatine in the liver, kidneys, and pancreas, storing it primarily in skeletal muscle tissue where it supports energy production and muscle protein synthesis