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Compared with GPX1-3, GPX4 is also involved in the reduction of complex membrane-associated phospholipid hydroperoxides such as phosphatidylcholine hydroperoxide and cholesterol hydroperoxide, in addition to reacting with soluble, low molecular weight hydroperoxides such as t-butyl hydroperoxide and cumene hydroperoxide [68]

Your response, your side effects, and your specific goals determine your optimal maintenance dose

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doi: 10.1038/s41580-023-00648-1 35 JiangXPengQPengMOyangLWangHLiuQet al