Quercetin was demonstrated to inhibit ferroptosis and improve joint cartilage destruction and degradation, delaying OA progression, by activating the AMP-activated protein kinase (AMPK)/Nrf2/GPX4 signaling pathway (Dong et al., 2025)
doi: 10.3389/fimmu.2019.02525
Modi, S
Note: Under no circumstances should people suddenly stop taking antidiabetic drugs, especially insulin
A meta-analysis have recorded that resveratrol dismantle this vicious cycle (chronic inflammation and oxidative stress) in PCOS mice, and improve levels of androgen, gonadotropin, and vascular endothelial growth factor (VEGF), as well as reduce endoplasmic reticulum stress in PCOS patients ( 5.1 Anti-inflammatory and anti-oxidative stress Previous research has founded that the serum levels of inflammatory markers, such as C-reactive protein (CRP), tumor necrosis factor (TNF-), interleukin 6 (IL-6), and IL-18, are significantly elevated in women with PCOS compared to healthy controls (89, 90)