Interestingly, gut-selective doses of sitagliptin retained the ability to improve glucose tolerance in mice with genetic ablation of DPP-4 from endothelial cells, albeit only in animals fed a chow diet and not those receiving a high-fat diet
Join us to connect, grow, and support one another as you work toward a more peaceful relationship with food and your body
Except for some symptoms such as headache and a few specific reactions (vomiting, vagal reactions, hypotension, discomfort, and arousal: one each) observed during alcohol and opioid withdrawal, DSIP has been well-tolerated during administration
Yet, other studies show a muscle atrophy-protecting effect (8, 9, 11)
How GLP-1-Based Medications Work GLP-1-based therapies - including compounded versions - work by enhancing the bodys natural appetite and glucose regulation processes: Appetite Signaling: Helps you feel full with less food Insulin Modulation: Encourages insulin release to manage post-meal blood sugar Gastric Delay: Slows stomach emptying, which can support smaller portion sizes These effects make GLP-1 medications a promising option for those looking to support long-term health with provider guidance
