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[1] [2] It belongs to an emerging class of metabolic medicines being studied for the treatment of obesity and type 2 diabetes mellitus by simultaneously targeting three distinct hormone receptor pathways
For weight management, other FDA-approved medications exist, including phentermine-topiramate and naltrexone-bupropion combinations
Circulation 2008;117:234050
Figure 4 Due to the influence of renal clearance and dipeptidyl peptidase-4 (DPP-4), GLP-1 has a short natural half-life in the human body, about 12 min (113)
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