The positive results were observed alongside weight loss and independently of it
Cell culture Human embryonic kidney cells (HEK293T, ATCC: CRL-11268), human cervical adenocarcinoma cells (HeLa, ATCC: CCL-2), Chinese hamster ovary cells (CHO-K1, ATCC: CCL-61), human telomerase-immortalized mesenchymal stem cells (hMSC-TERT), baby hamster kidney cells (BHK-21, ATCC: CCL-10) were cultured in Dulbeccos modified Eagles medium (DMEM
14,15 Potential Direct Effects on the Heart Although the systemic indirect effects of GLP-1RAs are well established as the primary drivers of their clinical benefit in HF, emerging preclinical and mechanistic evidence suggests GLP-1RAs may also exert some direct cardioprotective effects, as discussed below
For each study included in the review, we extracted detailed information on the study design, sample size, participant characteristics, type and dosage of GLP-1 RA used, and the key outcomes measured
Anjana RM, Sudha V, Lakshmipriya N, et al
