Complement genes contribute sex-biased vulnerability in diverse disorders
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Overall, it is recommended that SSRIs be avoided in male patients of childbearing age, whereas their use during IVF appears to be reasonable in women with depression or anxiety disorders ( 3 Effects of SSRIs on embryonic development Exposure to any SSRIs such as citalopram, paroxetine, and sertraline at any time during pregnancy has been shown to increase the risk of fetal mortality (Figure 2) ( postpartum hemorrhage may also be increased
PubMed, Ishiguro, Junko, et al
Despite promising in vitro and in vivo efficacy, validation remains limited to two cell lines and animal models