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The precursor for acetylation modification is acetyl-CoA, and classical acyltransferases and deacetylases are believed to catalyze all acetylation modifications and deacetylation modifications, including non-classical acyltransferases such as dihydrolipoamide S -acetyltransferase (DLAT) at the same time (Fig

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12 However, recent studies have shown that GST also takes part in promoting multidrug resistance in p53-mutated lung cancer cells