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Some who traditionally would fear injections are willing to try a weekly pen when they hear about significant weight improvements

Trials that started with lower initial doses and escalated more gradually showed reduced nausea severity compared to earlier protocols that escalated faster

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Protein quality control (PQC) systems at the ER include the unfolded protein response (UPR), ER-associated degradation (ERAD), and ER-phagy, which monitor ER homeostasis and contribute to protein refolding, sequestration, or degradation