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These signaling molecules mediate communication pathways through which the gut microbiota modulates the host's neuroendocrine system, forming what is commonly referred to as the gut-brain axis (Teichman et al., 2020) or the gut microbiota-metabolite-neuroendocrine axis (Wang J

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HDAC11 regulates glycolysis through the LKB1/AMPK signaling pathway to maintain hepatocellular carcinoma stemness

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In landmark mouse studies, oral 5-amino-1MQ produced robust reductions in adipocyte size, body fat and inflammatory adipokines while leaving food intake unchanged pointing to a fundamentally novel metabolic-rejuvenation mechanism that operates entirely on the methylationNAD axis

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