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In summary, the effects of DPP-4i on BP occur in a highly context-dependent manner, and the mechanisms of DPP4-i in regulating BP are summarized in Figure 1

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Current studies suggest that hyperglycemia is associated with a variety of poor clinical outcomes, and critically ill patients with hyperglycemia have a higher mortality rate than patients with normal blood glucose ( Statements Author contributions FY and FZ: Writingoriginal draft, XL, XH, JL, YL, and SL: Validation, XH: RL and YL review and editing

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95% Confidence Interval = 3.4-5.6